The 2022 Mercedes-Benz E-Class E 450 is equipped with front pedestrian automatic emergency braking, front automatic emergency braking, pedestrian detection pre-collision warning system, driver attention alert system, audible warning pre-collision warning system, visual warning pre-collision warning system, sensor/alert blind spot safety, rear multi-view camera system, premium brakes, driver knee airbags, front side airbags, rear side curtain airbags, front side curtain airbags, regenerative braking system, 4-wheel abs, emergency braking preparation, cornering brake control, auto-locking power door locks, painted brake calipers, brake drying, auto off electronic parking brake, crosswind stabilization, ventilated disc rear brake, alarm anti-theft system, braking assist, hill holder control, ventilated disc front brake, dual front airbags, vehicle immobilizer anti-theft system, power brakes, latch system child seat anchors, electronic brakeforce distribution, stability control, traction control, in dash rearview monitor, occupant sensing passenger airbag deactivation, front seatbelt pretensioners, front seatbelt force limiters, front emergency locking retractors, post-collision safety system impact sensor, rear seatbelt pretensioners, rear seatbelt force limiters, battery disconnect impact sensor, door unlock impact sensor, front seatbelt warning sensor, fuel cut-off impact sensor.